Lodha Machine is a leading manufacturer and exporter of industrial ethylene oxide sterilizer machines, which are highly demanded in various industries, including pharmaceuticals, food, herbals, agrochemicals, and chemicals. Our industrial ethylene oxide sterilizer machines are designed to meet the stringent requirements of these industries, assuring effective sterilization processes.
Industrial ethylene oxide (EO or ETO) gas is commonly used to sterilize objects sensitive to temperatures greater than 60 °C and/or radiation, such as plastics, optics, and electronics. The ethylene oxide treatment process is generally carried out between 30°C and 60°C with a relative humidity above 30% and a gas concentration between 200 and 800 mg/l. This process typically lasts for at least three hours. Ethylene oxide penetrates well, moving through paper, cloth, and some plastic films, making it highly effective. An ETO sterilization machine can kill all known viruses, bacteria, and fungi, including bacterial spores, and is compatible with most materials used in medical devices, even when repeatedly applied. It is important to note that ethylene oxide is highly flammable, toxic, and carcinogenic.
The ethylene oxide sterilization process involves four primary variables: gas concentration, humidity, temperature, and time. Ethylene oxide acts as an agent that disrupts the DNA of microorganisms, preventing them from reproducing. This assures that a safe and sterile product is delivered to the market each and every time. Industrial ethylene oxide sterilizer machines are designed to perform low-temperature, chemical sterilization treatments for medical, food, and pharmaceutical products sensitive to temperature and humidity. Ethylene oxide is a highly efficient sterilizing reagent that works as a bactericide, viricide and sporicide. Its favorable diffusion coefficient makes it suitable for thermo-sensitive or very delicate materials.
In the pharmaceutical industry, the use of ETO sterilization machines has been limited due to the high mutagenic and carcinogenic properties of ethylene oxide. Good Manufacturing Practices (GMPs) specify that this type of sterilization should only be used when there is no alternative sterilization technology available. Despite these risks, the advantages of ethylene oxide sterilization are significant, particularly in the hospital single-use product industry. Leading companies in this sector rely on ethylene oxide for the terminal sterilization of syringes, probes, catheters, pacemakers, and other complex medical devices. The penetrability of the sterilizing agent is critical for these devices, and ethylene oxide is far superior to alternatives like hydrogen peroxide and peracetic acid.
Lodha Machine has been manufacturing and exporting high-quality industrial ethylene oxide sterilizer machines to the global pharmaceutical industry for over 29+ years. We have established a strong reputation for delivering quality and efficient pharmaceutical machines, assuring customer satisfaction with every product we deliver. Our commitment to quality and innovation makes us a preferred choice for industrial ethylene oxide sterilizer machines globally.
Health Care Industry: Syringes, catheters, cartridges, dialysis equipment, sutures, IV sets, plastic products, heat-sensitive rubber items, and surgical gloves.
Pharmaceutical Industry: Thermostable base pharmaceutical products and chemical compounds.
Food Industry: Spices and herbs.
The process operation of an industrial ethylene oxide sterilizer machine involves several key steps. Ethylene oxide sterilization offers distinct advantages over conventional steam sterilizers, being a dry and cold process operating at approximately 50 oC. This makes it particularly useful for sterilizing expensive and delicate items, such as cardiac catheters, stents, IOLs, tubing, various types of scopes, and sharp surgical instruments. The unique penetration ability of ethylene oxide allows it to effectively sterilize these items without damaging them. The sterilizing procedure starts with loading the goods into the sterilizer chambers. The chamber is then evacuated to remove air and moisture, creating an ideal environment for the ethylene oxide gas. The gas is introduced into the chamber at the specified concentration, and the temperature and humidity are carefully controlled to assure optimal conditions for sterilization. The sterilization cycle typically lasts between three and four hours, depending on the specific requirements of the items being sterilized.
After the sterilization cycle is complete, the ethylene oxide gas is evacuated from the chamber using a series of vacuum and purge steps. This removes any residual gas and assures that the sterilized items are safe to handle. The items are then aerated to allow any remaining traces of ethylene oxide to dissipate. This oxygen procedure might take anything from a few hours to many days, depending on the materials and things getting sterilized. The entire process is monitored and controlled using advanced instrumentation and control systems, assuring consistent and effective results. By utilizing ethylene oxide sterilization, industries can effectively sterilize complex and sensitive products, extending their lifespan and assuring their safety for use.
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Our company offers complete packaging lines and processing equipment used in the production, quality control and formulation labs of pharmaceutical, dietary supplements, food, cosmetic and chemical industries. We offer a full range from production scale to small batch manufacturing equipment ideal for liquids, injectables, tablets, capsules, powders, creams and ointments.
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